Center for Clinical Diagnostics
- About Us
- Our Research
Personalizing Pediatric Care Through Innovative Diagnostics
The Center for Clinical Diagnostics at Nemours Children’s advances pediatric health care through innovative laboratory research and testing. We bridge clinical practice and research by developing and implementing specialized diagnostic assays to meet the unique needs of children.Ìý
Located in Delaware Valley, our team provides high-complexity testing focused on transplant immunology, gastroenterology, and autoimmune disorders. We use the latest technologies, including multiplexed immune assays, polymerase chain reaction (PCR), and next-generation sequencing. Our results inform diagnosis, treatment, and condition management.Ìý
In addition to testing services, we collaborate with researchers, participate in clinical trials, and publish impactful findings so that kids everywhere can benefit.Ìý
Our work has led to new insights and assays for detecting problems like organ transplant rejection, graft-versus-host disease, viruses, and gut inflammation.Ìý
Moving Research Forward: By the Numbers
With a proven track record of research excellence and innovation, the Center for Clinical Diagnostics advances pediatric medicine to improve outcomes for children.Ìý
$1.3 MÌýÌý
Revenues over cost by our Transplant and ImmunologyÌýResearch labs
$1.2 MÌýÌý
Revenues generated by our Gastroenterology Clinical Lab
3
Diagnostic labs in our center
We areÌýself-funding center that works with clinicians to identify, develop, and implementÌýhigh-complexity specialty tests.
We’veÌýdeveloped innovative transplant monitoring assays, and implemented rapid COVID-19 testing, directly impacting children's health worldwide.
OurÌýresearch explores crucial areasÌýin transplant rejection, autoimmune disorders, and gastrointestinal disease.Ìý
We’reÌýrecognized for our passion to advance children’s health and well-being.ÌýOur leadership was awarded Researcher of the Year at ÐÇ¿Õ´«Ã½ for his contributions.Ìý
Leadership Team
Paul T. Fawcett, PhD
Director, Center for Clinical Diagnostics
Principal Research Scientist
Join Us
Advancing Pediatric Medicine Through Specialized Diagnostics
Our research transforms laboratory discoveries into practical diagnostic solutions for children. Our work enables more precise and personalized pediatric care.
Focus Areas & Themes
Our center focuses on developing and offering high-complexity pediatric diagnostic testing. Our mission is to bring the latest research advancements to clinical practice, improving patient care through innovative lab testing.ÌýWe focus on:
- Transplant monitoring: Developing and performing specialized tests to support transplant patients, such as assays to monitor for infection, rejection, and graft-versus-host disease.Ìý
- Autoimmunity and inflammation: Creating autoantibody profile panels to facilitate faster diagnosis and management of systemic autoimmune disorders, lupus, vasculitis, and rheumatoid arthritis.Ìý
- Gastroenterology health: Advancing diagnostic testing for gastrointestinal and nutritional issues like enzyme deficiencies, gut inflammation, and pulmonary impacts.
- Researcher collaboration: Identifying needs and opportunities for new pediatric tests.
Laboratory Research
Our research labs develop and validate cutting-edge diagnostic tests across key areas. Our goal is to translate promising biomarker discoveries and analytical methods into clinically useful tests that allow for a more personalized diagnosis and treatment. Specific research involves:Ìý
- Measuring cytokines involved in transplant rejection
- Optimizing autoantibody testing using multiplex assays to diagnose autoimmune conditions
- Validating stool and blood tests for digestive enzyme deficiencies, celiac disease markers and gut inflammation
- Leveraging technologies like PCR, ELISA, and Luminex platforms
Clinical Trials & Research Studies at ÐÇ¿Õ´«Ã½
Pediatric clinical trials and research studies are important for advancing medical knowledge and improving care for kids around the world. Our researchers lead clinical research to study new drugs, treatments, devices, and techniques. We also contribute to national registries and collaboratives to further research in this area. Find a clinical trial or study now.
ResearchÌýPartnerships
We expand our knowledge and leverage diverse perspectives with partnerships and collaborations within and outside our field of study.Ìý
We work with ÐÇ¿Õ´«Ã½ specialists in orthopedics, rheumatology, gastroenterology, solid organ transplant, and bone marrow transplant. Our team also collaborates with Children’s Hospital of Philadelphia.Ìý
Related Research & Clinical Focus
Centers at ÐÇ¿Õ´«Ã½ often align with research areas, affiliated labs, and clinical programs to support discovery and care systemwide.Ìý
Blood Disorders Research
RESEARCH AREA
We explore blood disorders in children to advance care and outcomes through innovation in diagnostics, treatment, and long-term disease management.
Cancer Research
RESEARCH AREA
Investigators study childhood cancers to improve diagnosis, treatment, and survivorship through discovery science, clinical trials, and systemwide collaboration.
Cardiac Research
RESEARCH AREA
Our researchers study congenital and acquired heart conditions to advance pediatric cardiology through innovation in diagnosis, treatment, and outcomes.
Clinical & Research Immunology Lab
DELAWARE VALLEY
Our lab provides antibody testing for pediatric autoimmune and immunological disorders using advanced methods and rapid, reliable results.
Gastroenterology Clinical Lab
DELAWARE VALLEY
Our team studies diagnostic tools and treatments for intestinal injury, pancreatic dysfunction, gastric reflux-related aspiration, celiac disease, and IBD.
Immunology Research
RESEARCH AREA
We investigate immune system function in children to advance understanding of autoimmune disease, allergy, immunodeficiency, and immunotherapy.
Pulmonology Research
RESEARCH AREA
Our teams explore lung development and respiratory disease to improve care for children through imaging, monitoring tools, and treatment innovation.
Transplant Diagnostic & Research Lab
DELAWARE VALLEY
Our lab advances pediatric care through innovative diagnostic testing and research that connects scientific discovery with clinical decision-making.