Immunology Research
Understanding & Retraining the Immune System
Nemours Children’s immunology research explores how the body protects itself and what happens when those defenses don’t work as they should. Our work includes both diagnostic science and therapeutic innovation. We’re identifying immune dysfunction in children and developing new treatments that help the immune system fight back.
Our researchers advance the science of childhood autoimmunity, allergy, inflammation, and immunotherapy. We study the immune response at the molecular level and in clinical care settings.Together, we’re working to improve how immune system disorders are diagnosed, treated, and ultimately understood.
Key Areas of Research
Autoimmune & Inflammatory Disorders |Studying how immune responses lead to conditions like lupus and rheumatoid arthritis and improving how we detect and track these diseases in kids.
Cytokine & Cell Signaling Pathways |Exploring how immune cells communicate, and how we can target those signals to understand or treat disease.
T Cell Engineering & Cancer Immunotherapy |Developing new T cell therapies, including CAR-T cells, to treat childhood cancers more safely and effectively.
Immunotherapy for Allergies |Creating cell-based treatments that stop the immune cells causing severe allergies like asthma and food reactions.
Checkpoint Targets & Immune Regulation |Discovering new immune system “off switches” that could lead to better treatments for cancer and inflammatory disease.
Clinical Trials & Research Studies
Pediatric clinical trials and research studies are important for advancing medical knowledge and improving care for kids around the world. Our researchers lead clinical research to study new drugs, treatments, devices and techniques. We also contribute to national registries and collaboratives to further research in this area. Find a clinical trial or study now.
Where Immunology Research Happens
Immunology research at ǿմý takes place in dedicated laboratories within our Delaware Valley campus. Our teams collaborate closely with clinical specialists and academic partners to move discoveries from the lab bench to bedside. Our research reaches across specialties, from rheumatology and infectious disease to oncology and allergy.
Related Research
Center for Clinical Diagnostics
DELAWARE VALLEY
We provide diagnostic testing services that support clinicians and researchers in diagnosing and monitoring pediatric diseases more effectively.
Clinical & Research Immunology Lab
DELAWARE VALLEY
Our lab provides antibody testing for pediatric autoimmune and immunological disorders using advanced methods and rapid, reliable results.
T Cell Immunology & Immunotherapy Lab
DELAWARE VALLEY
Our lab develops CAR-T cell therapies and identifies new immune targets to advance treatment for pediatric cancers and immune disorders.
Immunology Clinical Care
Allergy & Immunology
CLINICAL CARE
Pediatric allergy and immunology care, including asthma and allergy testing, available at ǿմý locations in the Delaware Valley and Florida.
Oncology
CLINICAL CARE
Expert care for children with cancer provided by ǿմý pediatric oncologists, offering diagnostics, treatment, and long-term survivorship support.