Annemarie C. Brescia, MD
RheumatologyInsurance Accepted
- Aetna Better Health PA Kids HMO
- Aetna HMO
- Aetna PPO/POS/EPO
- Amerihealth Caritas Delaware
- AMERIHEALTH CARITAS DELAWARE VIP NEXT
- Carefirst MD Community Health Plan Mcaid
- Cigna Lifesource Transplant
- Cigna/Great West HMO EPO POS
- Cigna/Great West PPO
- Delaware Medicaid/Diamond State
- Delaware Medicare
- Devon Health Services
- Fidelis Care NJ Medicaid HMO
- First Health/Affordable PPO
- Geisinger Health Plan Commercial
- Global Medical Managment DE/PA
- Health Partners Medicaid/Kidz Partner HMO
- Highmark Blue Cross Blue Shield of Delaware
- Highmark Medicaid Health Options
- Horizon Blue Cross Blue Shield of New Jersey
- Independance Blue Cross/Amerihealth/Keystone Health Plan
- Insurance Administrators of America
- INTEGRA Administrative Group (ClaimsBridge)
- Keystone First CHIP
- Keystone First Medicaid HMO
- Lifetrac Transplant
- Maryland Medicaid
- Multiplan PPO
- National Transplant (Humana)
- New Jersey Medicaid
- Pennsylvania Medicaid
- Plan Vista/NPPN PPO
- Preferred Healthcare PPO
- Priority Partners John Hopkins
- Private Health Care Systems (PHCS)
- Qualcare HMO/POS/PPO
- Six Degrees Health-Tribado
- Tricare/Humana Military Health Services/CHAMPVA
- United Healthcare HMO/POS/PPO/EPO
- UPMC Medicaid/CHIP
- US Family Health Plan
- Wellpoint Maryland Medcaid
- Juvenile Idiopathic Arthritis
- Juvenile Rheumatoid Arthritis
Research Activities
I am the Principal Investigator of the Translational Rheumatology Research Laboratory, with our studies focusing on the cells that line the joint, the synovial fibroblasts, and their role in inflammatory arthritis.
Medical Interests
I am interested in caring for patients with all pediatric rheumatic diseases.
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Methotrexate inhibits BMP4 and abrogates the hypertrophic chondrocyte phenotype of synovial fibroblasts in juvenile idiopathic arthritis; Pediatric Rheumatology; (2024).
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Adalimumab Effectively Decreases Inflammation Downstream of TNFα Signaling in Synoviocytes from Extended Oligoarticular Juvenile Idiopathic Arthritis; Rheumatology and Therapy; (2023).
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CCL24, CXCL9 and CXCL10 are increased in synovial fluid in patients with juvenile idiopathic arthritis requiring advanced treatment; Rheumatology (United Kingdom); (2023).
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An Atypical Case of Scurvy in an Adolescent With Sacroiliitis; Clinical Pediatrics; (2022).
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Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype; Arthritis Research and Therapy; (2022).
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The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes; Pediatric Rheumatology; (2021).
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Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases; Journal of Clinical Investigation; (2020).
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Juvenile Idiopathic Arthritis Fibroblast-like Synoviocytes, through BMP signaling, play a central role in joint growth disturbances; Research Square; (2020).
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Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation; Pediatric Rheumatology; (2020).
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Prior to extension, transcriptomes of fibroblast-like synoviocytes from extended and polyarticular juvenile idiopathic arthritis are indistinguishable; Pediatric Rheumatology; (2018).
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Unilateral Periorbital Swelling in Two Previously Healthy Females; Global Pediatric Health; (2017).
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Secretion of pro-inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast-like synoviocytes in juvenile idiopathic arthritis; Proteomics - Clinical Applications; (2017).
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The role of transforming growth factor β signaling in fibroblast-like synoviocytes from patients with oligoarticular juvenile idiopathic arthritis: dysregulation of transforming growth factor β signaling, including overexpression of bone morphogenetic protein 4, may lead to a chondrocyte phenotype and may contribute to bony hypertrophy.; Arthritis & rheumatology (Hoboken, N.J.); (2014).
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Lyme chondritis presenting as painless ear erythema; Pediatrics; (2013).
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Prognostic Impact of Atypical Presentation in Pediatric Systemic Lupus Erythematosus: Results from a Multicenter Study; Journal of Pediatrics; (2010).
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Prolonged synovitis in pediatric lyme arthritis cannot be predicted by clinical or laboratory parameters; Clinical Rheumatology; (2009).
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Focus on Subspecialties, Importance of Immunizations:; AAP News; (2009).
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Predicting duration of beneficial effect of joint injection among children with chronic arthritis by measuring biomarkers concentration in synovial fluid at the time of injection; Clinical and Experimental Rheumatology; (2008).
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Steady improvement of prothrombin levels after cyclophosphamide therapy in pediatric lupus anticoagulant hypoprothrombinemia syndrome (LAHPS); Clinical Rheumatology; (2007).
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Joint Swelling; Pediatrics on Call; (2006).
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Process for the Preparation of Bis(Amidocarboxylic Acids); Unknown Source; (1995).
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Process for the Prepartion of Bis(Amidocarboxylic Acid); Unknown Source; (1995).
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One-pot synthesis of cyclic amidinium tetrafluoroborates and hexafluorophosphates; the simplest models of N5, N10-methenyl-tetrahydrofolate coenzyme; Tetrahedron Letters; (1991).
- English